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This transgene expresses a Multiple Sclerosis patient-derived HLA DRB5*01:01-restricted myelin basic protein (83-99) specific TCR (TCR alpha and beta chains of the TL3A6 TCR). TL3A6 expresses Valpha9.2-Jalpha12-Calpha and Vbeta5.1-D-Jbeta1.2-Cbeta. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:189816)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
