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Mice carrying the Cetn2tm1Wbae allele were crossed with an EIIa-Cre driver to eliminate the neo cassette and delete exons 2 and 3. Truncated mRNA (encompassing exons 1, 4, and 5) was detectable by RT/PCR but at very low levels (5-10% of wild-type). The truncated protein was undetectable in mutant olfactory epithelia by immunostaining, indicating that this is a null allele. (J:211061)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
