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The transgenic construct includes an EFGP translation initiation codon, signal peptide and human SQSTM1 (p62) translation initiation codon, signal peptide, termination codon and polyA tail. The 97 kD fusion protein is under the control of the Thy1.2 promoter. Expression is detected mainly in the hippocampal region of the brain and to a lesser extent in the brain stem, striatum, and cortex. (J:198513)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
