The targeting vector contains lox2272 (loxP variant) sites flanking exons 2 and 3 of the gene, and variant flpe recognition sequences flanking a PGK-HYGRO cassette downstream of the first lox2272 site. This allele was generated in ES cells containing Hamptm1Ddhf on the same chromosome. (J:220227)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count