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The H-2Kb promoter drives expression of the cytoplasmic portion of Lrp5 fused to two tandem AP20187 drug binding domains for chemically induced dimerization and the click beetle red-shifted luciferase gene. qRT-PCR confirmed expression of the transgene in multiple tissues of adults, with highest expression in the pancreas, followed by testes, mammary gland, spleen and prostate. (J:184212)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
