A loxP site was inserted upstream of the microRNA. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the microRNA. Flp-mediated recombination remoced the selection cassette and left the microRNA floxed. This allele was used to generate Mir34atm1Hher. (J:175978)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
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--
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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