Exon 2 was replaced with lacZ and neo cassettes. Beta-galactosidase is not expressed. Western blot analysis confirmed absence of protein expression in extracts of paw skin. Expression of two genes adjacent to Slurp1, Slurp2 and Lypd2, are reduced by 60-70% in homozygous mice. (J:210836)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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