Log In|Sign Up
EN
Exons 3 and 4 were deleted and replaced by a betageo/puro cassette, with only 21 bp of exon 3 remaining. This was confirmed at the genomic and RNA level. The construct contains a premature stop codon in the first 8 bp of the selection cassette, which is predicted to lead to a truncated 206 amino acid protein lacking presumably the immunoglobulin-like (Ig-like), serine-rich, fibronectin III, transmembrane and PDZ-binding domains. (J:214644)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
