A loxP site was inserted upstream of exon 5. Cre-mediated recombination removed the floxed hygromycin resistance cassette inserted downstream of exon 6. Exons 5 and 6 remain floxed. (J:213823)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count