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EN
Cre-mediated excision of the parental Pip4k2ctm1a(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exons (exons 3 and 4), leaving behind the inserted lacZ reporter sequence. Western blot analysis of kidney tissue confirmed the absence of protein expression in homozygous mutant mice. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739, J:234283)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
