A Dll1 minigene (exons 1 to 9 as cDNA followed by the remainder of the Delta1 gene intron 9, exon 10, intron 10, and exon 11) with nucleotide substitutions that result in the amino acid substitutions of valine for threonine at postition 638 (T638V) and alanine for serine at positions 693 (S693A) and and 696 (S696A) and a floxed neomycin resistance cassette were inserted downstream of exon 1. Cre-mediated recombination removed the selection cassette. (J:213529)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
8
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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