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The transgene is composed of the RP23_165_D11 BAC with the cre recombinase gene inserted at the translation start site of the 210 kb Fev fragment by an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. Passenger genes in the BAC include Cdk5r2, Cryba2, Ccdc108, Ihh and Nhej1. Founder FF3, FF9 and FM3 were generated. (J:218991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
