The targeting construct replaced the stop codon of exon 12 with an viral 2A self-processing peptide, EGFP reporter gene, a second viral 2A self-processing peptide, tamoxifen-inducible cre fusion gene (cre/ERT2) and FRT-flanked neomycin resistance cassette (2A-eGFP-2A-CreERT2-PGKneo). Flp-mediated recombination removed the selection cassette. (J:213957)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top