A loxP site was inserted upstream of exon 1 and a floxed neo selection cassette was inserted in intron 1. Exon 1 was excised using a viral vector expressing cre. The neo selection cassette remained. (J:212964)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count