The endogenous locus was targeted with two rounds of homologous recombination that inserted a floxed neomycin selection cassette into intron 1 and a cassette containing a floxed puromycin resistance gene followed by the lacZ reporter gene fused to a nuclear localization signal (nls-lacZ) into the 3' untranslated region. Exons 2 through 9 were flanked by the floxed selection genes. (J:210236)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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