A LacZ-FRT-neo-FRT cassette was inserted to replace 3' portion of exon 1 and entire sequences of exons 2 and 3. Immunoblot analysis of newborn brain lysates confirmed the absence of expression in homozygous mutant mice. (J:210612)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count