A loxP site was inserted upstream of exon 2 (at site 10310) and an FRT flanked neo cassette and loxP site were inserted downstream of exon 4 (at site 12190) via homologous recombination. Flp mediated recombination removed the neo cassette. PCR of a spontaneous mutation in the C57BL/6J Cd1d2 gene confirmed integration in the C57BL/6J allele. (J:210436)
Basic Information
(129S6/SvEvTac x C57BL/6J)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count