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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Igk
tm1.1(IgkAb2-1.4)Bbo
Alias:
VJk
aId
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Basic Information
Phenotypes
References Literature
The J kappa 1-5 regions were replaced with a floxed neo cassette and the rearranged VJ kappa region of the L chain of the anti-idiotope (Id+ M315 Ig) mAb Ab2-1.4. Cre mediated recombination removed the neo cassette. (J:209958)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5617053
BALB/c
Targeted
Insertion, Intragenic deletion
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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