Exon 6 was replaced with a floxed cDNA encoding exons 6-16, the 3' UTR and a 6x polyA signal, followed by exon 6 fused to a GFP reporter gene and an FRT flanked neo selection cassette in the inverse orientation. Flp mediated recombination removed the neo cassette. (J:183852)
Basic Information
(C57BL/6 x 129P2/OlaHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count