Exons 5-9 of the gene are flanked by loxP sites and followed downstream by an additional copy of exon 5 carrying a G184S mutation. An FRT-flanked neomycin resistance cassette was placed 3'. FLP mediated recombination removed the FRT-flanked neo cassette. (J:217517)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count