Exons 5-9 of the gene are flanked by loxP sites and followed downstream by an additional copy of exon 5 carrying a G184S mutation. An FRT-flanked neomycin resistance cassette was placed 3'. FLP mediated recombination removed the FRT-flanked neo cassette. (J:217517)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
Insertion
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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