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The transgenic construct contains a human eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) promoter/enhancer elements driving expression of a wildtype flag-tagged human src homology 2 domain-containing transforming protein C1 (SHC1) cDNA. The SHC1 sequence is fused to an internal ribosome entry site (IRES)-enhanced green fluorescent protein (EGFP) fusion protein, and is preceded by a loxP-flanked SV40 polyadenylation signal. (J:118108)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
