A loxP site flanked lacZ and neomycin resistance gene cassette was inserted downstream of the Shh enhancer in intron 5 of the Lmbr1 gene. Expression of lacZ is seen in the expected pattern at the posterior margin of the limb. (J:208849)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count