A cassette was inserted into the locus consisting of the CAG promoter, intron, floxed stop sequence, mouse Foxn1 cDNA fused to an ERT2 element, an IRES, and a GFP sequence. Cre mediated recombination is needed to induce protein expression. Protein activity in the presence of tamoxifen is similar to the endogenous protein. (J:208852)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count