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Using BAC recombineering roughly 3 Mbp of the mouse locus including all of the Vk and Jk segments was replaced with 480 kb of human IGK sequence including the proximal Vk and all of the Jk human gene segments. The final selection cassette was removed by flp-mediated recombination. (J:208619)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
