A Myc epitope tag, an IRES lacZ expression cassette and an FRT flanked PGK-neo were inserted downstream of the single exon. LoxP sites were inserted to flank the entire modified gene. The expression cassette was subsequently excised using flp recombinase. (J:208266)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count