A region encompassing the 5' UTR through intron 2 was replaced with a construct containing CAG-loxP-stop-loxP-Glra3 cDNA (rat, long variant with a P185L substitution and containing exon 8a) and human HPRT promoter and exons 1 and 2. The CAG-Glra3 and Hprt sequences are expressed in opposite directions. The Glra3 sequence also has an HA tag. (J:207981)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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