This allele from project Pcdh12-6034J-P3MB was generated at The Jackson Laboratory by injecting Cas9 nickase RNA and guide sequences GTAGCATCATGCTTACCGGC and CATTCCTGCTAGGGCTCTTA, which resulted in a 38 bp deletion GCCATTCCTGCTAGGGCTCTTAGGGCCAGGAAGCTACT in exon1 beginning at Chromosome 18 negative strand position 38,284,057 bp (GRCm38). This mutation is predicted to cause amino acid sequence changes after residue 5 and early truncation 63 amino acids later. (J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
3
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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