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A targeting vector containing a 2.0-kb cDNA fragment encoding exons 9 through 19 and a neo cassette was used to disrupt exons 8 through 12. Elimination of the alternative transcription start site in intron 10 results in expression of the full length (FL) mRNA transcript, but not the short-form (SF) transcript. RT-PCR analysis on spleen, bone marrow, and testis detected only long form transcript. (J:215969)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
