Cd22^m2Btlr

The crullers mutation is in Cd22: a T to C transition at base pair 30,869,883 (v38) on chromosome 7, or base pair 10,460 in the GenBank genomic region NC_000073. This corresponds to nucleotide 2,045 in the mRNA sequence NM_009845 within exon 8 of 14 total exons or nucleotide 2,170 in the mRNA sequence NM_001043317 in exon 10 of 16 total exons. The mutation results in a serine (S) to proline (P) substitution at position 603 (S603P) in both CD22 isoforms. (J:215821)