A loxP site was inserted 5' of the first exon and a frt-loxP-flanked neomycin (neo) cassette was inserted downstream of the coding sequence. The neo cassette was removed via flp-mediated recombination. (J:215207)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count