The targeting vector was designed to insert a loxP site upstream of the promoter, and a frt-flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 2 of the gene. FLP mediated recombination removed the FRT-flanked neo cassette. (J:215815)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count