This transgene has (from 5' to 3') a modified Tet response element (TRE or tetO), a mouse ubiquitin protein ligase E3A (Ube3a) cDNA sequence encoding transcript variant 2 (NM_011668.2), and an SV40 polyA signal. The Ube3a sequence has a FLAG epitope tag attached to its 5' end. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count