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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Gt(ROSA)26Sor
tm1(ACTB-Map2k5*/EGFP)Zxi
Alias:
ROSA caMEK5-eGFP
loxP
caMEK5-eGFP
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Basic Information
Phenotypes
References Literature
A construct consisting of a chicken beta-actin promoter, a floxed pgk-neo stop cassette, and a cDNA encoding a constitutive active Map2k5 fused in frame at the 3' end of an EGFP cDNA was inserted via homologous recombination. (J:206948)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5605718
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion, Intragenic deletion
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2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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