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The bacterial artificial chromosome (BAC) RP11273G3 from the Childrens Hospital Oakland Research Institute contains the entire human PRL gene, including the pituitary and extrapituitarypromoters as well as 115 kbp upstream and 38 kbp downstream of the gene-encoding sequences. Purified DNA was used for pronuclear microinjection into fertilized C57Bl/6J X DBA2 hybrid mouse oocytes. Two founder lines were produced (BAC-h8 and BAC-h30). (J:204079)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
