This transgene is driven by the cytomegalovirus (CMV) immediate-early (IE) enhancer, and the chicken beta actin promoter with an intron that drives widespread expression of an Mdm4 cDNA, an internal ribosomal entry site (IRES), the lacZ gene, and an SV40 poly(A) sequence. (J:164225)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count