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A loxP site was introduced 5' of the targeted gene's single exon and an FRT-loxP-(neo-tk)-FRT-loxP (LFNT) cassette was introduced 3'. The floxed exon was deleted by transient transfection of a Cre recombinase expression vector in the ES cells. (J:211355)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
