The transgenic construct contains Aimp1 sequence, derived from Methylcholanthrene A (Meth A)-transformed mouse fibrosarcoma cells and encoding mature secreted EMAPII protein, fused to an IFN-beta signal peptide sequence, under the control of the tetO, tetracycline-responsive regulatory element (seven copies of the 42-bp tet operator sequence placed between two minimal CMV enhancer-less promoters). (J:173904)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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