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A triple polyadenylation sequence and neomycin resistance cassette were inserted into the 3' end upstream of the Ube3a antisense transcript (chr7:66573289 NCBI37/mm9). The selection cassette is in the opposite orientation. qPCR confirmed the absence of transcript beyond the insertion site expression and unsilenced Ube3a transcript expression when the allele is inherited paternally. Maternal transcript expression is not affected. (J:207499)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
