KH2 ES cells were retargeted with a "flp-in plasmid" containing a tetracycline responsive element (TRE or tetO) and a forced dimerization fusion cDNA of Jun lacking the stop codon and Fosl2 connected by a flexible short polyGly-Ser peptide with a C-terminal FLAG-tag. A flpe-recombinase plasmid facilitated integration into the 3' UTR region. (J:210545)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count