A loxP site was inserted upstream of exon 16. An FRT-flanked neomycin resistance cassette with a 3 loxP site was inserted downstream of exon 19. Flp-mediated recombination removed the selection cassette and left exons 16 through 19 floxed. (J:207891)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count