The transgene was designed with a membrane-anchored green fluorescent protein (mEGFP), which carries a Ras membrane localization (CAAX) sequence in the carboxy terminus of EGFP, driven by a 3.9-kb 2',3'-cyclic nucleotide 3' phosphodiesterase (Cnp) promoter, followed by a human beta-globin polyadenylation site. Five lines were generated that displayed similar levels of expression. This is a representative record for all lines. (J:213410)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count