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The human involucrin promoter (promoter, exon 1 and intron1) drives the expression of the human KLK5 cDNA fused to the FLAG tag in the granular layer of the epidermis. Western blot confirmed expression in epidermal extracts and immunostaining confirmed protein expression in the upper epidermis. The pound symbol (#) is used when line is not specified. (J:210758)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
