The human prepro-orexin (HCRT) promoter drives the expression of 0.7 kb of the mammalianized tetracycline-controlled transcriptional activator (tTA). In situ hybridization on brain slices confirmed expression in orexin neurons. Lines 29, C5, and G5 show the highest tTA mRNA expression. (J:212974)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count