A lox66 was inserted upstream of exon 2. An inverted STOP element and lox71 site was inserted downstream of exon 2. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted between exon 2 and 3. Cre-mediated recombination restores the orientation of the STOP element and inverts exon 2. (J:209284)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Inversion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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