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The construct was designed to insert (from 5' to 3') an FRT site, the chicken beta-actin promoter (CAG), a loxP flanked stop cassette, the human IDH2 with the R172K mutation, a PGK hygro-polyA sequence, and a second FRT site into the mouse collagen A1 locus. (J:209629)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
