The single coding exon was flanked with loxP sites. An FRT-flanked neomycin resistance cassette was inserted downstream of the coding exon. Flp-mediated recombination removed the selection cassette and left the coding exon floxed. (J:207904)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count