A loxP site was introduced to intron 3 and a FRT-PGK-Neo-pA-splice donor-FRT-loxP cassette was placed in intron 4. Flpe mediated recombination removed the FRT-flanked neo cassette leaving loxP sites on either side of exon 4. (J:211681)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count