A loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:212451)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count