Log In|Sign Up
EN
Exons 25 and 26 were replaced with the sequence for human exon 26 and 27 with the deep intronic Leber Congenital Amaurosis-causing mutation (c.2991+1655AG). Cre-mediated recombination removed a floxed neomycin resistance cassette inserted downstream of human exon 27. (J:209218)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
