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EN
TALEN technology was used to generate an A to G point mutation in exon 26 that results in the amino acid substitution of aspartic acid for asparagine at position 1768 (N1768D). Seven more synonymous changes within the TALEN binding sites were introduced to minimize redigestion of targeted allele. 62 founders were identified with 13 distinct insertion/deletions in 24 mice. (J:207931)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
